Matthew Perry’s cause of death was revealed as the “acute effects of ketamine,” which contributed to him falling unconscious and drowning in a hot tub at his Los Angeles home. The autopsy from the Los Angeles County Medical Examiner’s Office ruled his death as accidental. Contributing factors included coronary artery disease and the impacts of the opioid buprenorphine, used for treating opioid use disorder. Matthew Perry was 54 years old at the time of his death in October 2023.
Perry was undergoing ketamine infusion therapy for depression and anxiety at the time of his death, with the last treatment occurring about a week and a half before his passing.
He had been sober for 19 months before Matthew Perry death and tested negative for alcohol and other drugs. The autopsy noted that the levels of ketamine in his system were higher than expected from the treatment, suggesting an overstimulation of the heart and slowed or shallow breathing as potential causes. Additionally, the heart disease and buprenorphine in his system may have exacerbated these effects. There were no drugs found near the pool/hot tub area, and prescription medications and loose pills were found elsewhere in his home. Matthew Perry, widely recognized for his portrayal of Chandler Bing in the television series “Friends,” had candidly shared his challenges with maintaining sobriety over the years.
What was the reason for Matthew Perry using ketamine?
Matthew Perry was receiving ketamine infusion therapy to treat his depression and anxiety. This treatment approach is used especially in cases where other more traditional methods might not have been as effective.
What is Ketamine?
Ketamine, commonly utilized for initiating and maintaining anesthesia, creates a trance-like state while offering pain relief and sedation, and can also result in temporary memory loss. Apart from its use in medical settings, ketamine has a history of abuse as a recreational drug due to its hallucinogenic and dissociative effects. It’s often referred to by the street name “Special K.” Ketamine can significantly affect the user’s perception of sight and sound and can lead to feelings of detachment from one’s environment and self. Additionally, in controlled medical settings, it’s being explored for its potential in treating depression.
Ketamine Effects
Ketamine, used in both medical and recreational settings, has various effects. Medically, it’s used as an anesthetic, causing pain relief, sedation, and memory loss. Recreationally, it can induce hallucinations and a sense of detachment from one’s environment and self. It affects perception, leading to altered sights and sounds. Higher doses can result in what’s known as a “K-hole,” a state of intense disconnection or dissociation from reality. It’s important to note that the effects of ketamine can vary greatly based on the dose and individual response.
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